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Weight-loss drug cuts risk of heart attack, strokes: Novo Nordisk
Danish pharma group Novo Nordisk's obesity drug Wegovy cuts the risk of heart attacks and strokes by a fifth, the company said in an announcement Tuesday that sent its shares soaring to a record high. Though preliminary, it is the first research to suggest this class of weight loss medication, which has attracted considerable attention from the wider public, can confer lasting improvements to cardiovascular health. The trial enrolled 17,604 adults aged 45 years who were either overweight or obese, and were randomized to receive either the injected drug, or a placebo, over a period of five years. Strokes, heart attacks, and cardiovascular death were reduced by 20 percent, Novo Nordisk said in a statement, though it did not offer a breakdown for each category. The detailed results of the trial will be presented at a scientific conference later this year, it said, adding that it plans to apply for regulatory approval to expand the uses for Wegovy in the United States and the European Union in 2023. Novo Nordisk's share price closed up by more than 17 percent on the Copenhagen stock exchange on Tuesday. "We are very excited about the results," the company's executive vice president for development Martin Holst Lange said, adding the drug "has the potential to change how obesity is regarded and treated". The medical community also welcomed the results. While the trials "still need to be confirmed through careful peer review, they demonstrate the urgent need for patients living with obesity to be offered this effective and safe drug to prevent future disease," said Simon Cork, senior lecturer in physiology at Anglia Ruskin University, who was not involved in the research. The results "are exciting as preventing heart attacks and stroke with a drug that also lowers weight is very important for many patients," added Naveed Sattar, a professor of metabolic medicine, University of Glasgow, who was also not involved in the research but has previously consulted for Novo Nordisk. Novo Nordisk, the world's biggest insulin maker which manufactures both Wegovy and diabetes drug Ozempic, in May announced a 39 percent rise in its first quarter profit, buoyed by sales of its obesity treatments. In mid-July, the Amsterdam-based European Medicines Agency said it was reviewing data "on the risk of suicidal thoughts and thoughts of self-harm" with three popular weight-loss drugs, Ozempic and Wegovy -- which both have semaglutide as their main ingredient -- and Saxenda, whose main ingredient is liraglutide. Competition among pharmaceutical groups over obesity treatments is fierce, with more than a billion people in the world suffering from obesity, according to the World Health Organization. The post Weight-loss drug cuts risk of heart attack, strokes: Novo Nordisk appeared first on Daily Tribune......»»
Trial to begin over foiled Paris train attack& nbsp;
A Moroccan man goes on trial in France on Monday accused of an attempted terror attack on an Amsterdam-Paris train five years ago which was foiled by passengers whose heroic actions were turned into a Hollywood film......»»
US reaffirms support for Philippines sovereignty amid its tensions with China
Washington, DC [US], March 28 (ANI): US Secretary of Defence Llyod Austin has reaffirmed Washington's commitment to Manila in defending its sovereignty while criticising China's "dangerous" water cannon attack at the Philippine supply mission vessel on Saturday. In a telephonic conversation between Austin and his Philippine counterpart Gilberto Teodoro, the US Secretary reiterated the US-Philippines Mutual Defence Treaty.....»»
NBA: James triple-double pulls Lakers past Grizzlies
LeBron James returned from a one-game absence to post a 23-point triple-double on Wednesday and lead the Los Angeles Lakers to a 136-124 NBA victory over the Memphis Grizzlies. James sat out the Lakers’ come-from-behind double-overtime victory over the Milwaukee Bucks on Tuesday with a sore left ankle. READ: NBA: Giannis tows Bucks over Thunder .....»»
Double pay for workers reporting on Holy Week
Workers nationwide may opt to enjoy a long holiday break or hefty pay this Holy Week......»»
Jihadists
For his own purposes, Vladimir Putin has been trying to link the deadly terrorist attack on a concert hall in Moscow to Ukraine. The casualty figure for that attack has now risen t.....»»
Russian Spy Chief Makes Bizarre Claim of US, UK, and Ukraine Involvement in Moscow Attack
In a recent development, the director of Russia’s Federal Security Service (FSB) has made startling accusations against Ukraine, the US, and the UK, claiming they.....»»
Philippines lodges strong protest with China over water cannon attack in disputed South China Sea
Manila [Philippines], March 25 (ANI): In the wake of accusation by the Philippines that the Chinese Coast Guard wounded three of its soldiers during a water cannon attack in the disputed South China Sea, Manila on Monday summoned Beijing's envoy to lodge its strong protest, Al Jazeera reported. The Philippines Department of Foreign Affairs, in a statement said that Manila conveyed its "strong protest against the aggressiv.....»»
Rice imports as of mid-March 886,963 MT
The country’s rice imports as of mid-March have surpassed the total volume recorded in the entire first quarter of last year by a double-digit rate, to over 880,000 metric tons, government data showed......»»
Andales cancels IBF world title fight in Japan
CEBU CITY, Philippines — Filipino ArAr Andales reportedly withdrew from his world title bout on March 31 in Nagoya, Japan. Andales was scheduled to fight the reigning International Boxing Federation (IBF) world minimumweight champion, Ginjiro Shigeoka of Japan. Their world title duel was supposedly a double-header world title bout with fellow Filipino Melvin Jerusalem gunning.....»»
2 hurt in another gun attack in Cotabato City
Two local residents were wounded in another ambush incident in this city at about 11:00 p.m. Monday......»»
Russian Media Accuses Ukraine of Moscow Concert Hall Attack – The Daily Guardia
In a shocking turn of events, President Putin has attributed the recent concert hall assault in Moscow to radical Islamists for the first time. However,.....»»
Philippines lodges strong protest with China over water cannon attack in disputed South China Sea
Manila [Philippines], March 25 (ANI): In the wake of accusation by the Philippines that the Chinese Coast Guard wounded three of its soldiers during a water cannon attack in the disputed South China Sea, Manila on Monday summoned Beijing's envoy to lodge its strong protest, Al Jazeera reported. The Philippines Department of Foreign Affairs, in a statement said that Manila conveyed its "strong protest against the aggressiv.....»»
Kyiv, Lviv under Russian air attack; missile violates Polish airspace
'The object entered Polish space near the town of Oserdow and stayed there for 39 seconds,' Poland's armed forces says on the social media platform X.....»»
Sharon Cuneta, KaladKaren remember Jaclyn Jose
“Megastar” Sharon Cuneta and TV host KaladKaren remembered the late actress Jaclyn Jose, who succumbed to heart attack last March 2 at 60 years old......»»
Man killed, wife wounded in Antipolo gun attack
A man was killed while his wife was wounded in a shooting in Antipolo City, Rizal on Wednesday night......»»
US warns China against armed attack on Philippines
Washington, DC [US], March 19 (ANI): US Secretary of State Antony Blinken warned China on Tuesday, stating that any "armed" attack on Philippine vessels in the South China Sea would activate a mutual self-defence agreement between Washington and Manila, underscoring the escalating tensions in the region that could potentially embroil the United States in conflict with Beijing, as reported by The New York Times. Despite th.....»»
Addressing the Philippines’ 2024 Threat Landscape: Kaspersky Launches KUMA Platform
To help Filipino businesses and organizations stay safe in cyberspace while embracing digitalization, Kaspersky announces today the launch of Kaspersky Unified Monitoring and Analysis Platform (KUMA), its integrated software solution that includes a set of functions for security information and event monitoring and management. The Philippines is expected to continue its double-digit growth towards $35B […].....»»
Red Sea, Gulf of Aden eyed as warlike zones
Amid escalating conflict and the recent death of two Filipino seafarers in a Houthi rebel missile attack, the Philippine government is strongly pushing for the declaration of the Southern Red Sea and Gulf of Aden as a warlike zone......»»
Suspected Houthi attack: Missile hits ship in Red Sea, crew reportedly safe
DUBAI, United Arab Emirates — A suspected attack by Yemen’s Houthi rebels struck a ship in the Red Sea early Friday, causing damage to the vessel, authorities said. The attack off the port city of Hodeida comes as part of the rebels’ campaign against shipping over Israel’s ongoing war on Hamas in the Gaza Strip......»»